Facial Aesthetics
Polynucleotides: Natural Skin Regeneration, Elevated
Polynucleotides are innovative bio-stimulating treatments designed to strengthen, repair and deeply rejuvenate the skin. Made from purified DNA fragments, they work to calm inflammation, stimulate collagen and elastin, support tissue healing and improve hydration — resulting in smoother texture, enhanced elasticity and an overall healthier, more radiant complexion. Over time, your skin becomes stronger, firmer and visibly revitalised from the inside out.
Before and Afters
Get In Touch With Us
At Define Clinic, polynucleotide treatments are performed by medical experts who specialise in advanced regenerative aesthetics. We take a personalised approach to treatment planning, ensuring your results look natural and harmonious with your features. If you’re looking for fresh, hydrated, glowing skin that lasts, we design a treatment journey that prioritises safety, subtlety and long-lasting skin health. Your results should feel like you — just refreshed, restored and radiant.
REVIEWS
Don’t just take our word for it
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The Define team make you feel welcome from the moment you enter the clinic. My Polynucleotide treatment was carried out with care by Dr.Arreni, she was thorough with her explanations and made me feel very relaxed during the procedures. I’m very happy with the outcome and would highly recommend Dr.Arreni if you are looking for natural, long-lasting results.
Leila
3rd September 2025
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It’s always special having a treatment at Define Clinic. Lovely staff whose care is always so through and thoughtful
Shirlie Kemp
19th August 2025
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Define is the best clinic in London. I would only trust Benji for my touch ups and Eden has completely transformed my skin with BBL. They are so incredibly friendly and I genuinely look forward to going to Define. I couldn’t recommend them more!
Amy Stewart
25th November 2024
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Beautiful clinic and amazing people! My special thank you to Dr Hena for her attention to detail and professionalism.
Olga Jarvis
16th October 2024
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If I had the choice of rating DefineClinic any higher, I definitely would!
All the staff there are lovely, respectful and always happy to help!
I had Dr Sunny & Faye to help and carry out my composite bonding journey.
From my first appointment they were so helpful, trying to gain an insight into what I want in order to achieve my dream smile.
I had my final appointment this week to polish and complete my smile, and I am over the moon with the results.
Couldn’t recommend DefineClinic enough!
Thank you all! :))Joe Gaskell
6th October 2024
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This was my first time ever getting any cosmetic procedure done, and I’m so glad I chose to have this experience done at define with Rosie. Going into my appointment, I was feeling a little apprehensive as to how my results were going to turn out. I just wanted something to help get rid of a few lines on my forehead without anyone noticing that I had anything done. Rosie took all of my points into consideration and she exceeded my expectations. Not only did she try to calm my nerves by bringing me water and making sure my experience was enjoyable, she also made sure that I was completely comfortable with everything she was doing and she made sure that I had all the knowledge I needed before I continued with the procedure.
One thing I will say about define, it’s a little on the pricier side however, it is worth every penny. You are paying for quality and good results!
If anyone is considering going to define (especially if this is your first cosmetic experience), I would highly recommend booking with the lovely Rosie!
Amelia Guida
23rd September 2024
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Simply the best 🚀
Simon Michael Carroll
14th September 2024
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I had the pleasure of visiting Dr Benji Dhillon this week at his stunning premises for some much needed lower face rejuvenation. I felt that during consultation, Benji knew exactly what I was aiming for; which was to feel and look better, but still natural and without being obvious. He has a wonderful manner, friendly and putting me at ease and the procedure was less daunting and painful than I thought. I was also impressed with how he talked me through the procedure, which I found very interesting! I am utterly thrilled with the results, and feel I look like ‘the old me.’ but in a very subtle way. I will go back to Benji in the future without a doubt and already planning my next visit.
Gemma Walsh – Face Rejuvenation
17th July 2024
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If I could give Define and all its wonderful and friendly staff a million stars I would! I could not have had a warmer and more understanding welcome and this continues throughout every visit I make on my treatment journey. The holistic care, expertise and professionalism is second to none and I look forward to every visit in this beautiful, state of the art clinic. I feel comfortable, relaxed and thoroughly looked after! The results achieved are natural and absolutely fantastic and I wouldn’t consider going anywhere else! Thank you to all at Define I’ve got my confidence back and feel a new woman!!
Amy B – General
17th July 2024
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I really appreciated how warm and welcoming Dr Berisha was during my appointments, which helped to put me at ease. She was also very knowledgable about the procedure and patiently answered all of my questions. I am very happy with the results and will be visiting Define clinic again soon!
Samantha Kent – General
17th July 2024